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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1322371
Species: Mus musculus
CRRD Object: Gene
Symbol: Gpr157
Name: G protein-coupled receptor 157
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDValproic Acid affects the expression of GPR157 mRNA

PMID:17963808
increases expressionISORGD:13223706480464CTDValproic Acid results in increased expression of GPR157 mRNA

PMID:23179753, PMID:24383497, PMID:24935251
increases methylationISORGD:13223706480464CTDValproic Acid results in increased methylation of GPR157 gene

PMID:29154799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.