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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1561852
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ap5s1
Name: adaptor related protein complex 5 subunit sigma 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ap5s1affects expressionISORGD:13450166480464CTDValproic Acid affects the expression of AP5S1 mRNA

PMID:25979313
Ap5s1decreases expressionISORGD:13450166480464CTDValproic Acid results in decreased expression of AP5S1 mRNA

PMID:29154799
Ap5s1increases expressionISORGD:13450166480464CTDValproic Acid results in increased expression of AP5S1 mRNA

PMID:28001369
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.