GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1565375
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cbx8
Name: chromobox 8
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISOCRRD:15580876480464CTDValproic Acid affects the expression of CBX8 mRNA

PMID:17963808
increases expressionISOCRRD:15580876480464CTDValproic Acid results in increased expression of CBX8 mRNA

PMID:19136453
increases methylationISOCRRD:13510036480464CTDValproic Acid results in increased methylation of CBX8 gene

PMID:29154799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.