Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 6766578
Species: Homo sapiens
CRRD Object: Gene
Symbol: A2M-AS1
Name: A2M antisense RNA 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
A2M-AS1affects expressionEXP 6480464CTDValproic Acid affects the expression of A2M-AS1 mRNA

PMID:25979313
A2M-AS1decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of A2M-AS1 mRNA

PMID:24383497, PMID:26272509
A2M-AS1increases methylationEXP 6480464CTDValproic Acid results in increased methylation of A2M-AS1 gene

PMID:29154799
A2M-AS1multiple interactionsEXP 6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of A2M-AS1 mRNA

PMID:27188386
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.