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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620561
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mt-nd6
Name: mitochondrially encoded NADH dehydrogenase 6
Acc ID: CHEBI:40968
Term: astaxanthin
Definition: A carotenone that consists of beta,beta-carotene-4,4'-dione bearing two hydroxy substituents at positions 3 and 3' (the 3S,3'S diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein.
Chemical ID: MESH:C005948
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7353866480464CTDastaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA]

PMID:16964424
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.