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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620018
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gzmb
Name: granzyme B
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13534956480464CTDTamoxifen results in decreased expression of GZMB mRNA, Tamoxifen results in decreased expression of GZMB protein

PMID:20145137
increases expressionISORGD:13534956480464CTD[Tamoxifen results in increased expression of TGFB1 protein] which results in increased expression of GZMB mRNA

PMID:20145137
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