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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737062
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKCA
Name: protein kinase C alpha
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7370636480464CTDTamoxifen affects the expression of PRKCA mRNA

PMID:17555576
decreases phosphorylationISORGD:7370636480464CTDTamoxifen results in decreased phosphorylation of PRKCA protein

PMID:19393235
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.