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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2018
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Acly
Name: ATP citrate lyase
Acc ID: CHEBI:42355
Term: erythromycin A
Definition: An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.
Chemical ID: MESH:D004917
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:100646480464CTDErythromycin results in increased expression of ACLY mRNA

PMID:27503388
multiple interactionsISORGD:100646480464CTD[Penicillin G co-treated with Erythromycin] results in increased expression of ACLY mRNA

PMID:27503388
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.