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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621883
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cnn1
Name: calponin 1
Acc ID: CHEBI:42977
Term: 25-hydroxycholesterol
Definition: A 25-hydroxy steroid that has formula 402.65294.
Chemical ID: MESH:C007997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD25-hydroxycholesterol results in increased expression of CNN1 mRNA

PMID:17161435
multiple interactionsEXP 6480464CTD15-deoxyprostaglandin J2 inhibits the reaction [25-hydroxycholesterol results in increased expression of CNN1 mRNA], alitretinoin promotes the reaction [25-hydroxycholesterol results in increased expression of CNN1 mRNA]

PMID:17161435
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.