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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 736171
Species: Mus musculus
CRRD Object: Gene
Symbol: Capn3
Name: calpain 3
Acc ID: CHEBI:4317
Term: dantrolene
Definition: The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin.
Chemical ID: MESH:D003620
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:22696480464CTDDantrolene results in decreased expression of CAPN3 mRNA, Dantrolene results in decreased expression of CAPN3 protein

PMID:11236903
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.