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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69152
Species: Homo sapiens
CRRD Object: Gene
Symbol: EGFR
Name: epidermal growth factor receptor
Acc ID: CHEBI:4357
Term: Deguelin
Definition: An isoflavanone that has formula C23H22O6.
Chemical ID: MESH:C107676
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDdeguelin metabolite results in decreased expression of EGFR protein, deguelin results in decreased expression of EGFR protein

PMID:19139008
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.