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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1312373
Species: Homo sapiens
CRRD Object: Gene
Symbol: LRP6
Name: LDL receptor related protein 6
Acc ID: CHEBI:43572
Term: kojic acid
Definition: A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae.
Chemical ID: MESH:C011890
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDkojic acid results in decreased expression of LRP6 mRNA

PMID:16595896
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.