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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1562456
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Skp2
Name: S-phase kinase associated protein 2
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:16070866480464CTDMethotrexate results in decreased expression of SKP2 mRNA

PMID:24657277
multiple interactionsISORGD:16070866480464CTD[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of SKP2 mRNA

PMID:24657277
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