GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620267
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: S100a9
Name: S100 calcium binding protein A9
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:13529816480464CTDMethotrexate results in decreased expression of S100A9 mRNA

PMID:17400583
increases expressionISOCRRD:13529816480464CTDMethotrexate results in increased expression of S100A9 mRNA

PMID:17696278
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.