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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730881
Species: Homo sapiens
CRRD Object: Gene
Symbol: HRAS
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:44368
Term: nitrofurazone
Definition: A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections.
Chemical ID: MESH:D009583
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:28276480464CTDNitrofurazone results in increased expression of HRAS mRNA

PMID:15945272
multiple interactionsISORGD:28276480464CTDAcetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of HRAS mRNA]

PMID:15945272
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.