GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1309799
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Hdac1
Name: histone deacetylase 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISOCRRD:13203306480464CTDtrichostatin A results in decreased activity of HDAC1 protein

PMID:15103026, PMID:15927959, PMID:15930892
decreases expressionISOCRRD:13203306480464CTDtrichostatin A results in decreased expression of HDAC1 protein

PMID:23285096
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.