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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 733705
Species: Homo sapiens
CRRD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDtrichostatin A results in increased expression of CTNNB1 mRNA

PMID:24935251, PMID:26272509
multiple interactionsEXP 6480464CTD[3-deazaneplanocin co-treated with trichostatin A] affects the expression of CTNNB1 protein, [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTNNB1 mRNA, trichostatin A inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein], trichostatin A inhibits the reaction [Dibutyl Phthalate affects the localization of CTNNB1 protein]

PMID:18538736, PMID:22552774, PMID:27188386
multiple interactionsISORGD:15504666480464CTD[estradiol dipropionate co-treated with trichostatin A] results in decreased expression of CTNNB1 protein

PMID:15930180
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.