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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1312683
Species: Homo sapiens
CRRD Object: Gene
Symbol: EZH2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDAcetaminophen affects the expression of EZH2 mRNA

PMID:25458485
increases expressionEXP 6480464CTDAcetaminophen results in increased expression of EZH2 mRNA

PMID:21420995, PMID:22230336, PMID:29067470
decreases expressionISORGD:13126846480464CTDAcetaminophen results in decreased expression of EZH2 mRNA

PMID:17942131
increases expressionISORGD:15958606480464CTDAcetaminophen results in increased expression of EZH2 mRNA

PMID:29665328
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.