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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620575
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7332946480464CTDAcetaminophen affects the expression of APAF1 mRNA

PMID:17562736
increases expressionISORGD:7332936480464CTDAcetaminophen results in increased expression of APAF1 mRNA

PMID:22230336
increases expressionISORGD:7332946480464CTDAcetaminophen results in increased expression of APAF1 mRNA

PMID:11752693
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.