GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 708428
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Akr1c3
Name: aldo-keto reductase family 1, member C3
Acc ID: CHEBI:46790
Term: 2-methoxyethanol
Definition: A hydroxyether that is ethanol substituted by a methoxy group at position 2.
Chemical ID: MESH:C005219
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDmethyl cellosolve results in decreased expression of AKR1C3 mRNA

PMID:21427058
multiple interactionsEXP 6480464CTDmethyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA]

PMID:21427058
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.