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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730973
Species: Mus musculus
CRRD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding factor 2
Acc ID: CHEBI:47499
Term: imipramine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Chemical ID: MESH:D007099
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7309726480464CTDImipramine results in increased cleavage of and results in increased activity of SREBF2 protein

PMID:16324787
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.