GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620707
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tff1
Name: trefoil factor 1
Acc ID: CHEBI:48347
Term: triclocarban
Definition: A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
Chemical ID: MESH:C009540
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:13446716480464CTDtriclocarban results in increased expression of TFF1 mRNA

triclocarban results in increased expression of TFF1 protein

PMID:24740835
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.