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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1306661
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chuk
Name: component of inhibitor of nuclear factor kappa B kinase complex
Acc ID: CHEBI:48574
Term: phenylbutazone
Definition: A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Chemical ID: MESH:D010653
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13154016480464CTDPhenylbutazone inhibits the reaction [TNF protein results in increased activity of CHUK protein]

PMID:15489888
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.