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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730858
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL2
Name: interleukin 2
Acc ID: CHEBI:48828
Term: cobalt(2+)
Definition: A cobalt cation that has formula 58.93320.
Chemical ID: MESH:D003035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases secretionEXP 6480464CTDCobalt results in decreased secretion of IL2 protein

PMID:25612073
multiple interactionsEXP 6480464CTD[tungsten carbide co-treated with Cobalt] results in increased expression of IL2 mRNA

PMID:18078969
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.