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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737062
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKCA
Name: protein kinase C alpha
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects localizationISORGD:33956480464CTDzinc chloride affects the localization of PRKCA protein

PMID:21575692
multiple interactionsISORGD:33956480464CTD1, 3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein], 1, 3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of PRKCA protein], Glucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein], Vanadates promotes the reaction [zinc chloride affects the localization of PRKCA protein], zinc chloride affects the localization of and results in increased activity of PRKCA protein

PMID:20800666, PMID:21575692
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.