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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730927
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL5
Name: interleukin 5
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDNanotubes, Carbon results in increased expression of IL5 mRNA

PMID:25511174
multiple interactionsEXP 6480464CTDNanotubes, Carbon inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]

PMID:23266719
affects expressionISORGD:107996480464CTDNanotubes, Carbon affects the expression of IL5 mRNA

PMID:23845593
decreases secretionISORGD:107996480464CTDNanotubes, Carbon results in decreased secretion of IL5 protein

PMID:19371758
increases expressionISORGD:107996480464CTDNanotubes, Carbon results in increased expression of IL5 mRNA, Nanotubes, Carbon results in increased expression of IL5 protein

PMID:19428951, PMID:22293422, PMID:25554681
multiple interactionsISORGD:107996480464CTD[Antigens, Dermatophagoides co-treated with Nanotubes, Carbon] results in increased expression of IL5 mRNA, [PTGS2 gene mutant form results in increased susceptibility to [Nanotubes, Carbon co-treated with OVAL protein]] which results in increased expression of IL5 mRNA

PMID:23642096, PMID:26091108
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.