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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2085
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:50673
Term: methimazole
Definition: A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen.
Chemical ID: MESH:D008713
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:101366480464CTDMethimazole results in decreased expression of ALB mRNA

PMID:29990518
decreases expressionISOCRRD:7354046480464CTDMethimazole results in decreased expression of ALB mRNA

PMID:29990518
multiple interactionsISOCRRD:7354046480464CTDMethimazole inhibits the reaction [IGF1 protein results in increased expression of ALB mRNA]

PMID:29990518
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.