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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2874
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:50729
Term: mitoxantrone
Definition: A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Chemical ID: MESH:D008942
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceISOCRRD:7360426480464CTDIGFBP3 protein affects the susceptibility to Mitoxantrone

PMID:16217747
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