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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 13975473
Species: Sus scrofa
CRRD Object: Gene
Symbol: CYP2C49
Name: cytochrome P450 2C49
Acc ID: CHEBI:50842
Term: norflurazon
Definition: A pyridazinone that is pyridazin-3(2H)-one which is substituted at positions 2, 4, and 5 by m-(trifluoromethyl)phenyl, chloro, and methylamino groups, respectively. A pre-emergence herbicide used to control grasses and broad-leafed weeds in a variety of crops. Not approved for use within the European Union.
Chemical ID: MESH:C008677
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2C49multiple interactionsEXP 6480464CTDCYP2C49 protein results in increased metabolism of and results in decreased susceptibility to norflurazone

PMID:16315095
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