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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 732487
Species: Homo sapiens
CRRD Object: Gene
Symbol: TGM2
Name: transglutaminase 2
Acc ID: CHEBI:50859
Term: bexarotene
Definition: A retinoid that has formula C24H28O2.
Chemical ID: MESH:C095105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDbexarotene results in increased expression of TGM2 mRNA

PMID:17178900
increases expressionISORGD:7324886480464CTDbexarotene results in increased expression of TGM2 mRNA

PMID:21622945, PMID:25932594
multiple interactionsISORGD:7324886480464CTDdiazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]

PMID:25932594
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.