Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1593189
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gsta5
Name: glutathione S-transferase alpha 5
Acc ID: CHEBI:50866
Term: 3H-1,2-dithiole-3-thione
Definition: A 1,2-dithiole that has formula C3H2S3.
Chemical ID: MESH:C049325
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD1, 2-dithiol-3-thione results in increased expression of GSTA5 mRNA

PMID:19695238
increases expressionISORGD:16201186480464CTD1, 2-dithiol-3-thione results in increased expression of GSTA1 mRNA

PMID:18367636, PMID:7568053
multiple interactionsISORGD:16201186480464CTDNFE2L2 gene mutant form inhibits the reaction [1, 2-dithiol-3-thione results in increased expression of GSTA1 mRNA], Tetradecanoylphorbol Acetate promotes the reaction [1, 2-dithiol-3-thione results in increased expression of GSTA1 mRNA]

PMID:18367636, PMID:7568053
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.