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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1347052
Species: Homo sapiens
CRRD Object: Gene
Symbol: MIR214
Name: microRNA 214
Acc ID: CHEBI:51211
Term: alprenolol
Definition: A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.
Chemical ID: MESH:D000526
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Alprenolol co-treated with ARRB1 protein] results in increased expression of MIR214 mRNA

PMID:24334028
increases expressionISORGD:16076766480464CTDAlprenolol results in increased expression of MIR214 mRNA

PMID:24334028
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.