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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 731265
Species: Mus musculus
CRRD Object: Gene
Symbol: Polr1b
Name: polymerase (RNA) I polypeptide B
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:6208226480464CTDFlutamide results in decreased expression of POLR1B mRNA

PMID:24793618
increases expressionISORGD:6208226480464CTDFlutamide results in increased expression of POLR1B mRNA

PMID:24136188
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.