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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69313
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:52497
Term: maneb
Definition: A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab.
Chemical ID: MESH:D008344
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDManeb results in decreased expression of ACHE protein

PMID:3868355
multiple interactionsISOCRRD:7358796480464CTD[LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of ACHE mRNA

PMID:23017109
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