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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730938
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKN
Name: parkin RBR E3 ubiquitin protein ligase
Acc ID: CHEBI:5298
Term: Genipin
Definition: An iridoid monoterpenoid that has formula C11H14O5.
Chemical ID: MESH:C007834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:620896480464CTDgenipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein], sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]]

PMID:28477916
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.