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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69313
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:5592
Term: HLo7
Definition: An organic molecular entity that has formula C15H17N5O4.2I.
Chemical ID: MESH:C058577
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDHLo 7 inhibits the reaction [Sarin results in decreased activity of ACHE protein]

PMID:16025528
decreases activityISOCRRD:7358786480464CTDHLo 7 results in decreased activity of ACHE protein

PMID:26210933
multiple interactionsISOCRRD:7358786480464CTDHLo 7 affects the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]

HLo 7 affects the reaction [S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate results in decreased activity of ACHE protein]

HLo 7 affects the reaction [Sarin results in decreased activity of ACHE protein]

HLo 7 affects the reaction [VX results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [dicrotophos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [dimethoxon results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [heptenophos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [malaoxon results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [methamidophos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [methyl demeton results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Soman results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [tabun results in decreased activity of ACHE protein]

HLo 7 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein]

PMID:18555982, PMID:19761810, PMID:20096273, PMID:25451328, PMID:26210933, PMID:8783813
multiple interactionsISOCRRD:7358796480464CTDHLo 7 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]

PMID:20385200
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.