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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620709
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tff2
Name: trefoil factor 2
Acc ID: CHEBI:5775
Term: hydralazine
Definition: The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Chemical ID: MESH:D006830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7313686480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of TFF2 mRNA

PMID:17183730
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.