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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1316317
Species: Mus musculus
CRRD Object: Gene
Symbol: Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Acc ID: CHEBI:6121
Term: ketamine
Definition: A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Chemical ID: MESH:D007649
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:6197916480464CTDKetamine results in decreased expression of BUB1B mRNA

PMID:20080153
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.