GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 67383
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Prkcd
Name: protein kinase C, delta
Acc ID: CHEBI:63041
Term: manganese(II) chloride
Definition: An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Chemical ID: MESH:C025340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDmanganese chloride results in increased activity of PRKCD protein

PMID:21310168
multiple interactionsEXP 6480464CTDmanganese chloride results in increased cleavage of and results in increased activity of PRKCD protein

rottlerin inhibits the reaction [manganese chloride results in increased activity of PRKCD protein]

PMID:21310168, PMID:25416158
multiple interactionsISOCRRD:690266480464CTDSNCA protein inhibits the reaction [manganese chloride results in increased cleavage of and results in increased activity of PRKCD protein]

PMID:25416158
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.