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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620800
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Bnip3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7338146480464CTD1-Methyl-4-phenylpyridinium results in decreased expression of BNIP3 mRNA, 1-Methyl-4-phenylpyridinium results in decreased expression of BNIP3 protein

PMID:17475336, PMID:18069091, PMID:22776087
increases expressionISORGD:13509136480464CTD1-Methyl-4-phenylpyridinium results in increased expression of BNIP3 mRNA

PMID:18266926
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.