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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 732487
Species: Homo sapiens
CRRD Object: Gene
Symbol: TGM2
Name: transglutaminase 2
Acc ID: CHEBI:64210
Term: 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid
Definition: An amidobenzoic acid obtained by formal condensation of the carboxy group of (5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)benzoic acid with the anilino group of 4-aminobenzoic acid. A selective RARalpha agonist.
Chemical ID: MESH:C068073
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDAm 580 results in increased activity of TGM2 protein

PMID:2884032
increases expressionEXP 6480464CTDAm 580 results in increased expression of TGM2 mRNA

PMID:16982809
multiple interactionsEXP 6480464CTD[Am 580 co-treated with CD 2425] results in increased activity of TGM2 protein

PMID:9516142
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.