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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620131
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Bdh1
Name: 3-hydroxybutyrate dehydrogenase 1
Acc ID: CHEBI:64227
Term: ciglitazone
Definition: An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Chemical ID: MESH:C039671
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7372896480464CTD[ciglitazone binds to PPARG protein alternative form] which results in increased expression of BDH1 mRNA

PMID:16197558
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.