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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3351
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Plin1
Name: perilipin 1
Acc ID: CHEBI:6451
Term: Licarin A
Definition: A benzofuran that has formula C20H22O4.
Chemical ID: MESH:C432503
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7362206480464CTD[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 mRNA, [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 protein, N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 protein], PRKACA protein promotes the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 protein]

PMID:29288687
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.