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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69037
Species: Homo sapiens
CRRD Object: Gene
Symbol: INA
Name: internexin neuronal intermediate filament protein alpha
Acc ID: CHEBI:6520
Term: lomustine
Definition: An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours.
Chemical ID: MESH:D008130
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDINA affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]

PMID:21246521
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