Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3322
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Phb
Name: prohibitin
Acc ID: CHEBI:65329
Term: LY294002
Definition: A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2.
Chemical ID: MESH:C085911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of PHB protein

PMID:23254195
multiple interactionsISORGD:7369486480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [PHB protein inhibits the reaction [FSHB protein results in increased secretion of Estradiol]], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [PHB protein results in decreased activity of FSHB protein]

PMID:23254195
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.