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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1316368
Species: Homo sapiens
CRRD Object: Gene
Symbol: ZEB2
Name: zinc finger E-box binding homeobox 2
Acc ID: CHEBI:67271
Term: MK-2206
Definition: An organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted at positions 8 and 9 respectively by 4-(1-aminocyclobutyl)phenyl and phenyl groups.
Chemical ID: MESH:C548887
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13163696480464CTDMK 2206 results in decreased expression of ZEB2 mRNA

PMID:30723155
multiple interactionsISORGD:13163696480464CTD[U 0126 co-treated with MK 2206] results in decreased expression of ZEB2 mRNA

PMID:30723155
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.