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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 731380
Species: Homo sapiens
CRRD Object: Gene
Symbol: AIFM1
Name: apoptosis inducing factor mitochondria associated 1
Acc ID: CHEBI:67272
Term: perifosine
Definition: A phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group.
Chemical ID: MESH:C105905
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[perifosine co-treated with Butyrates] results in increased secretion of AIFM1 protein, [perifosine co-treated with trichostatin A] results in increased secretion of AIFM1 protein, [perifosine co-treated with vorinostat] results in increased secretion of AIFM1 protein

PMID:15781658
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.