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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2414
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cryab
Name: crystallin, alpha B
Acc ID: CHEBI:6736
Term: melittin
Definition: A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.
Chemical ID: MESH:D008555
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDMelitten promotes the reaction [sodium arsenite results in increased expression of CRYAB mRNA], Melitten promotes the reaction [sodium arsenite results in increased expression of CRYAB protein]

PMID:8591993
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.