GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1309438
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Map3k7
Name: mitogen activated protein kinase kinase kinase 7
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13197826480464CTD[Paclitaxel co-treated with Metformin] results in decreased expression of MAP3K7 mRNA

PMID:29309887
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.