GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3447
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ptpn11
Name: protein tyrosine phosphatase, non-receptor type 11
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDMethoxychlor results in increased expression of PTPN11 mRNA

PMID:21782745
multiple interactionsEXP 6480464CTD[Genistein co-treated with Methoxychlor] results in increased expression of PTPN11 mRNA

PMID:21782745
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.